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Alpha Lipoic Acid Plus

Alpha Lipoic Acid is a potent antioxidant, which destroys more "free radicals" than other antioxidants, and enhances other antioxidant activity, especially Vitamins C and E. Alpha Lipoic Acid Plus includes Vitamin C and E along with the powerful antioxidant, Pine Bark Extract to enhance this Alpha Lipoic Acid formula.

 

Each capsule contains:
Alpha Lipoic Acid - 100mg; Vitamin C (Ascorbic Palmitate) - 5 mg; Vitamin E (Natural E) - 20 IU; Pine Bark Extract - 10mg.

  • Alpha Lipoic Acid enhances the activity of other antioxidant, preventing the oxidative damage of "free radicals", which are associated with the process of aging and major health problems, such as heart disease, diabetes, cancer, cataracts etc.

  • Alpha Lipoic Acid is a naturally occurring co-factor in the body found most abundantly in red meat, however, there are generally small insufficient amounts in our bodies.

  • It is both water and fat soluble making it very bioavailable.

  • Alpha Lipoic Acid helps to regulate blood sugar levels, and has been used as a treatment for diabetes in Europe for over 30 years.

  • It has a positive effect on many disorders including diabetes, heart conditions, metal poisoning and radiation damage.

  • Alpha Lipoic Acid provides antioxidant protection against LDL's, helping to prevent fatty deposits on arterial walls.

  • May help to prevent cataract formation.

  • Desiccant pads are included in Alpha Lipoic Acid Plus, as well as in all of Montiff's highest quality nutraceutical Products, to insure optimal freshness.

WHAT IS ALPHA LIPOIC ACID (ALA)?

  • A naturally occurring co-factor in the body, found most abundantly in red meat.
  • It exists in variety of locations in the body: intracellular, extra-cellular and membranes.
  • Many individuals have insufficient amounts.
  • Its reduced form is Dihyrolipoic Acid (DHLA), and it is essential for metabolic process of energy (ATP) from food.
  • A potent antioxidant that destroys more ‘free radicals” than other antioxidants.
  • A chelator of heavy metal ions, such as copper and iron as well as toxic metal such as cadmium, lead and mercury.
  • Lessens oxidative damage caused by radiation exposure, and was used effectively in the former Soviet Union after the Chemobyl incident.
  • Being both water and fat-soluble makes it very bioavailable.
  • ALA (also known as Thioctic acid) increases Glutathione levels in the cells, and enhances the activity of other antioxidants, especially E and C.
  • It has had positive effects on many disorders, including diabetes, heart conditions, cataracts, metal poisoning, and radiation damage.

FUNCTIONS:
As a very effective antioxidant, ALA helps prevent the oxidative damage caused by free radicals, which are associated with the process of aging and major health problems, such as heart disease, diabetes, cancer, arthritis, cataracts and asthma.

    DIABETES

  • ALA has been used safely for the treatment of diabetics in Europe for over 30 years in doses of 300-600 mg. daily. Antioxidants such as ALA and glutathione prevent neuropathies associated with diabetes.

    CARDIO-VASCULAR:
  • lschemia-reperfusion injuries, which occur in conditions such as stroke, cardiac arrest and head trauma, result from the release of free radicals during reoxygenation of tissue that has become hypoxic.
  • ALA:  is efficacious in preventing Ischemia-reperfusion injuries, and may be important to patients who have strokes, cardiac infarction, and open heart surgery.
  • ALA provides antioxidant protection against LDL’s, helping to prevent fatty deposits on arterial walls.

    AIDS AND HIV:
  • ALA is effective in its antioxidant action, preventing complications to patients with compromised immune systems, such as AIDS and HIV patients.
  • By enhancing antioxidants Vitamins E and C and producing Glutathione, ALA and DHLA enhance the immune response of HIV patients who are deficient in most antioxidants.
  • These antioxidants scavenge free radicals that are responsible for inactivating white blood cells necessary as a defense against foreign bodies, may help inhibit replication of the virus and also help block the activation of the virus.

    CATARACTS:
  • ALA enhances activity of glutathione, Ascorbate and vitamin E levels, which have an effect on cataract prevention.

    STIMULATES MUSCLE STRENGTH AND ENERGY:
  • ALA may decrease nitric oxide release, and enhances the uptake of glucose into the muscle, prevents glycation of proteins and is essential for ATP production.

    IMPROVES NERVOUS SYSTEM AND MEMORY:
  • Alpha Lipoic Acid protects the mitochondria of cells in the brain and nervous system, and it may be involved in nerve regeneration.

    IMPROVES LONGEVITY BY SLOWING THE AGING PROCESS:
  • Inhibits oxidation and glycation, which cause the accelerated aging process in skin, blood vessels and connective tissue.

WHAT ARE THE BENEFITS OF ALPHA LIPOIC ACID PLUS?

  • Montiff uses the highest quality ingredients and includes desiccant pads to insure freshness.
  • Alpha Lipoic Acid Plus combines ALA with other antioxidants (vitamins C, E and Pine bark extract) to potentiate its effectiveness.
  • Pine bark extract is an antioxidant that helps prevent nitric oxide deficiencies.
  • Alpha Lipoic Acid is easily absorbed and readily bioavailable.

SAFETY
Alpha Lipoic Acid has been safely used for over 30 years in Europe in doses of SQ0-600mg., with no significant adverse effects. With individuals who are thiamin deficient, such as alcoholics, thiamin (B-i) supplements may be advised. Since no studies have been reported on pregnant women, it is not recommended for them.

REFERENCES:

  1. Nichols, Trent W.,"a-Lipoic Acid: Biological Effects and Clinical Implications"., Alt. Med. Rev. 1997.
  2. Packer, Lester et al., "Alpha-Lipoic Acid-the Metabolic Antioxidant", Free Rad. Biol Med., 1996.
  3. Snodderly, Max, "Evidence for Protection Against Age-Related Macular Degeneration by Carotenoids and Antioxidant Vitamins", Am. J. Clin Nutr., 1995.
  4. Wolff, Simon P. et al, "Thioctic (Lipoic)Acid: A Therapeutic Metal Chelating Antioxidant"?, Biochem Parmacol., 1995.
  5. Ziegler, Can and Gries, Arnold, "a-Lipoic Acid in the Treatment of Diabetic Peripheral and Cardiac Autonomic Neuropathy", Diabetes, 1997.
  6. Streeper, Ryan S., et al,. "Differential Effects of Lipoic Acid Stereoisomers on Glucose Metabolism in Insulin-Resistant Skeletal Muscle", Am. J. Physiol., 1997.
  7. Jahn, G. Baur A, et al., " Alpha Lipoic Acid is an Effective Inhibitor of Human Immun0-Deficiency Virus (HIV-1) Replication. Klin Wochenser, 1991.
  8. Jacob, S. et al., "Enhancement of Glucose Disposal in Patients with Type 2 Diabetes by Alpha-Lipoic Acid", Drug Res., 1995.
  9. Klip, Amira et al,. "Stimulation of Glucose Uptake by the Natural Coenzyme-Lipoic Acid/Thioctic Acid", Diabetes, 1996.
  10. Packer, Lester et al.,"Neuroprotection by the Metabolic Antioxidant a-Lipoic Acid", Free Rad. Biol. Med., 1997.
  11. Serbinova, E., Maitra, I and Packer L., "The Synergy Between Vitamin E and Alpha-Lipoic Acid-Possible in Protection of Against Oxidative Stress in Vivo", Life Chemistry Reports, 1994.
  12. Sies, Helmut et al., "Antioxidant Activity of Dihydrolipoate Against Microsomal Lipid Peroxidation and its Dependence on a-Tocopherol", BiochemistryBiophys. Acta., 1989.
  13. Podda, M. et al., "a-Lipoic Acid Supplementation Prevents Symptoms of Vitamin Deficiency", Biochem. Biophys Res. Comm., 1994.
  14. Shi, X. Chen, F. et al., "One- Electron Reduction of Chromium (VI) by a-Lipoic Acid and Related Hydroxyl Radical Generation, dG Hydroxylation and Nuclear Transcription Factor-B Activation", Arch. Biochem Biophys., 1997.
  15. TappIn, K., Basu et al, Antioxidants in Human Health and Disease, 1999.

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Glossary

Column

Amino Acids - are the building blocks of protein. Your body is primarily made of protein.  And protein in turn, is made up of chains of amino acids What distinguishes all amino acids is that they all have a group, (amine group), made of 1 atom of nitrogen & 2 atoms of hydrogen. (NH2)

Free-Form Amino Acids - Individual amino acids that are  unattached to each other or anything else & therefore able to be immediately absorbed into the blood stream with no digestion necessary. Since, unlike proteins, free-form amino acids require absolutely no digestion, they can be absorbed by anyone no matter how old they may be or the condition of their digestive system.  Also, unlike proteins, free-form amino acids can be taken on an empty stomach such as right before a workout.  Whereas proteins have to have a mass of food sufficient to stimulate the release of digestive juices. This is why most protein supplements are presented as blender drinks.  Free-form amino acids are not to be confused with so-called "predigested protein." which is not really predigested but actually partially digested.

Negative nitrogen balance - The condition of excreting more amino acids & protein than one is taking in. This makes it difficult to maintain ones body since the body's tissues are mainly made of protein & amino acids which require constant maintenance & repair.

Precursors - the substance from which another substance is made.

Protein - Chains of some combination of the 20 so-called "proteogenic" amino acids. (proteogenic means to generate protein). In other words their are only 20  amino acids from which all proteins in all organic life both animal & vegetable are made. Not all 20 are in every protein, but nothing else but some portion of the 20 proteogenic amino acids in repetitive long chains often approx. 100,000 amino acids long are what all proteins in all life are made from.

Secretalogical cells - Cells that secrete hormones.