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Glossary

Column

Amino Acids - are the building blocks of protein. Your body is primarily made of protein.  And protein in turn, is made up of chains of amino acids What distinguishes all amino acids is that they all have a group, (amine group), made of 1 atom of nitrogen & 2 atoms of hydrogen. (NH2)

Free-Form Amino Acids - Individual amino acids that are  unattached to each other or anything else & therefore able to be immediately absorbed into the blood stream with no digestion necessary. Since, unlike proteins, free-form amino acids require absolutely no digestion, they can be absorbed by anyone no matter how old they may be or the condition of their digestive system.  Also, unlike proteins, free-form amino acids can be taken on an empty stomach such as right before a workout.  Whereas proteins have to have a mass of food sufficient to stimulate the release of digestive juices. This is why most protein supplements are presented as blender drinks.  Free-form amino acids are not to be confused with so-called "predigested protein." which is not really predigested but actually partially digested.

Negative nitrogen balance - The condition of excreting more amino acids & protein than one is taking in. This makes it difficult to maintain ones body since the body's tissues are mainly made of protein & amino acids which require constant maintenance & repair.

Precursors - the substance from which another substance is made.

Protein - Chains of some combination of the 20 so-called "proteogenic" amino acids. (proteogenic means to generate protein). In other words their are only 20  amino acids from which all proteins in all organic life both animal & vegetable are made. Not all 20 are in every protein, but nothing else but some portion of the 20 proteogenic amino acids in repetitive long chains often approx. 100,000 amino acids long are what all proteins in all life are made from.

Secretalogical cells - Cells that secrete hormones.

"Never go past a misunderstood word because you will blank out & not understand anything you read after that misunderstood word." (L.Ron Hubbard)  Therefore every Information Page will have a Glossary Column to the right.  Glossary words will be bolded, underlined & colored green.  Since this site is still under construction & all glossary items are not complete call tech support if you need further explanation.  Additional note: Discounts are available which due to the competitive nature of the internet we do not wish to put up on this website. Once again just call the 800#.
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Montiff Information Page on

Pure Glycine
Glycine is involved with gluconeogenesis and is necessary for proper glucose balance, collagen formation and for healthy central nervous function.

 

Each capsule of Pure Glycine contains
500 mg of pure, highest quality Glycine.

RECOMMENDED TO ENHANCE STRUCTURE & FUNCTION RELATING TO NUTRITIONAL NEEDS AND DEFICIENCIES PERTAINING TO:

  • Promotes Gluconeogenesis.

  • Formulation of collagen, and found in skin and connective tissue.

  • Promoting synthesis of creatine to help prevent degeneration of muscle tissue and may have an effect on Muscular Dystrophy and other degenerative muscular disorders.

  • Central nervous system by functioning as an inhibitory neurotransmitter and may have an effect on Epilepsy.

  • Improper metabolism involved in non-Ketotic Hyperglycemia.

  • Participating in the synthesis of purines, porphyrins, and glyoxylic acid.

  • Prostate health.

  • Involved in bile acid metabolism and gastrointestinal function.

WHAT IS GLYCINE?
Glycine is a non-essential amino acid synthesized in the body through various complex pathways involving Threonine, Serine, Hydroxyproline and Choline metabolism. It is involved in the synthesis of purines, porphyrins, creatine and glyoxylic acid, and is also a biochemical constituent of the tripeptide glutathione. Glycine is also essential for the synthesis of bile and nucleic acids, and it is used in many commercial gastric antacid preparations. It is important in the central nervous system where it acts as one of the main inhibitory neurotransmitters. Although high amounts of Proline and 4-hydroxyproline are found in collagen (important for skin and connective tissue), almost 1 third is comprised of Glycine. High amounts of Glycine are found in gelatin, which is a denatured collagen. Low plasma levels of Glycine are noted in Hypoglycemics, those with viral infections and fevers, CFS (Chronic Fatigue Syndrome) and anemia. A metabolic disorder causing excessive levels of Glycine in the spinal fluid is responsible for Non-Ketotic Hyperglycemia, or Rett Syndrome, which has symptoms of autism.

GLYCINE AND GLUCONEOGENESIS
Glycine is considered a glucogenic amino acid, which includes others such as Glutamine, Alanine, Threonine, Serine, Methionine, Tyrosine, and Lysine, and thus is involved in maintaining blood sugar levels. Hypoglycemics are low in Glycine and supplementation with Glycine, along with other glucogenic amino acids, is beneficial in regulating low blood sugar levels, and increasing energy in those who are lethargic due to this condition.

GLYCINE AND NEUROLOGICAL EFFECTS
Glycine is one of the main precursors to inhibitory neurotransmitters, along with Taurine, GABA, and other such as Tyrosine, Phenylalanine, Serine and Threonine.

  • SCHIZOPHRENIA
    Research regarding supplementation with Glycine, along with traditional medications (antipsychotics), appear to have beneficial results with Schizophrenics, although less effective when combined with clozapine.

     

  • GLYCINE AND MEMORY AND ATTENTION
    Because of its receptor sites, Glycine appears to be beneficial in memory. In a double- blind crossover study, both young and middle-aged men significantly benefited with improved episodic memory. It was suggested that supplementation with Glycine could significantly improve memory that may be impaired due to jet lag, disrupted sleep, or work fatigue, and be helpful in memory retrieval problems associated with schizophrenia, Parkinson's disease and Huntington's disease.

     

  • GLYCINE AND ANTICARCINOGENIC PROPERTIES
    In a preliminary study over a 55-week period (published in 1999), Glycine was administered to animals with hepatic cancer. The results indicated that Glycine prevented the formation of small tumors by 23%, inhibited the development of medium tumors by 64% and prevented the formation of the largest tumors by nearly 80%. The study conclusion was that Glycine might be an effective chemoprotective agent. In another study published in1999 with animals with melanomas, those fed with Glycine had 50-70% less tumor size then the control group. This study concluded that dietary Glycine prevents tumor growth in vivo by inhibiting angiogenesis via the inhibition of endothelial cell proliferation.

 

  • GLYCINE AND GROWTH HORMONE LEVELS
    Studies have indicated significant increase in growth hormone levels on those who were administered between 4-12 grams of Glycine.

OTHER BENEFITS OF GLYCINE:

  • Increases creatine synthesis. Glycine, along with Arginine supplementation, increases endogenous creatine synthesis.

  • Acute ischaemic stroke. A study of patients administered 1-2 grams of Glycine sublingually, within 6 hours after the onset of acute ischaemic stoke in the carotid artery, indicated favorable clinical effects.

WHAT ARE THE BENEFITS OF MONTIFF PURE GLYCINE?

  • Montiff supplies the highest quality pure Glycine available in 500 mg capsules for fast assimilation.

  • Desiccant pads are provided to insure optimal freshness.

REFERENCES:

  1. Di Pasquale, M, Amino Acids and Proteins for the Athlete, the Anabolic Edge, 1997.

  2. Cynober, Luc (edited by), Amino Acid Metabolism and Therapy in Health & Nutritional Disease, 1995.

  3. Balch, J. M.D., Balch, P., C.N.C., Prescription for Nutritional Healing, 1997.

  4. Gusev, Skvortsova et al., "Neuroprotective Effects of Glycine for Therapy of Acute Ischaemic Stroke", Cerebrovasc Dis., Jan.-Feb.2000.

  5. Rose, Cattley, Dunn, wong et al, Univ. of N. Carolina, "Dietary Glycine Prevent the Develop. Of Liver Tumors Caused by the Peroxisome Proliferator WY-14, 643", Carcinogenesis, Nov. 1999.

  6. Rose, Madren et al, U. of N. Carolina, " Dietary Glycine Inhibits the Growth of B 16 Melanoma Tumors in Mice", Carcinogenesis, May 1999.

  7. Kasai, Kobayashi, Shimoda, "Stimulatory Effect of Glycine on Human Growth Hormone Secretion", Metabolism, 1978.

  8. Banay-Schwartz, Palkovitis, Lajtha, " A Heterogeneous Distribution of Functionally Important Acids in Brain Areas of Adult and Aging Humans". Neurochem. Res., 1993.

  9. Evins, Fitzgerald, Wine, Rosselli, Goff, Mass. Gen. Hospital , "Placebo-Controlled Trial of Glycine to Clozapine in Schizophrenia", Am. J. Psychiatry, May 2000.