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Liver-Protec
DIRECTIONS: Take 2-4 capsules per day, or as needed, as part of a
daily nutritional program.
RECOMMENDED TO ENHANCE STRUCTURE & FUNCTION RELATING TO NUTRITIONAL
NEEDS AND DEFICIENCIES PERTAINING TO:
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Enhancing liver function.
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Protecting healthy cells from free radical damage.
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Stimulating Glutathione production.
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Helping to detoxify harmful chemical substances.
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Providing liver support against damage from alcohol.
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Stimulating new liver cell production.
The liver is the largest organ in the body and is responsible for
detoxifying harmful substances in the body, including drugs,
pollutants, alcohol, chemicals and other foreign matter. The liver
also has many other functions. It converts digested food into
proteins, fats and carbohydrates and stores sugar as glycogen. It also
manufactures cholesterol (80% of it used to make bile), and substances
necessary for clotting blood. There are two types of malfunctions
manifesting in liver problems. One type involves malfunctions of the
liver cells, such as Hepatitis or Cirrhosis. The other malfunction is
caused by obstructions of the bile flow through the biliary tract,
which transport the toxic elements out of the body into the blood
stream and eventually excreted in the urine. These obstructions are
caused by gall stones or cancer. The ingredients in Liver -Protec help
support healthy liver function and help prevent against oxidative
damage to healthy liver cells.
THE BENEFICIAL INGREDIENTS IN LlVER-PROTEC ARE:
SILYMARIN EXTRACT: Silymarin, which comes from the milk thistle
plant, has three flavonoid molecules and is considered to be an
important hepatoprotectant. It stimulates new liver cell production,
as well as replacing damaged liver cells -acting on both hepatic
stellate cells and myofibroblasts. It also acts as a strong
antioxidant, helping to prevent free radical damage. It has been shown
to increase Glutathione in the liver, which is responsible for
detoxifying many chemicals, such as lead, mercury, cadmium and arsenic
and alcohol, as well as protecting against tetrachloride &
galactosamine. Silymarin is beneficial for liver function and provides
liver support in relationship to cirrhosis, chemical or alcohol
induced fatty liver, and hepatitis.
ALPHA LIPOIC ACID:
ALA is a potent antioxidant, which helps
protect against free radical damage.
It
also helps increase Glutathione in the
liver, which is important to detoxify heavy metals, alcohol, hydrogen
peroxide and other chemicals and harmful substances. Tobacco and
especially alcohol deplete Glutathione levels. The painkiller
acetaminophen can also deplete Glutathione, which is why there have been
warnings not to take this painkiller when consuming alcohol. This
combination can cause a serious reduction of Glutathione resulting in
severe problems to the liver. There is a constant demand for Glutathione
in the body, especially during illness, and Alpha Lipoic Acid is one of
the best sources for enhancing its production.
d-ALPHA TOCOPHERYL SUCCINATE: Various forms of vitamin E are
known to be effective antioxidants, protecting healthy cells from free
radical damage. d-Alpha Tocopheryl Succinate is an important form of
Vitamin E and has been shown to reduce tumor growth in some cancers and
works well in conjunction with standard cancer therapies.
QUERCETIN DI-HYDRATE: A bioflavonoid found in onions, tea, green
leafy vegetables, beans and red wine. It induces hydrogen
peroxide apoptosis and protects DNA from oxidative free radical damage.
Studies suggest it may have an effect on tumor cancer growth.
CALCIUM D-GLUCARATE : A form of glucaric acid, a natural compound
found in the body with detoxification properties. It helps by
detoxifying harmful carcinogenic pesticides, such as DDT and Atrazine.
It also inhibits Beta-Glucuronidase, an enzyme in the intestinal tract.
High levels of Beta-Glucuronidase are associated with common duct
gallstones and certain cancers.
REFERENCES:
1. Packer, Lester, Ph.D., Colman, C,
The Antioxidant Miracle, 1999.
2. Bustamonte, J., et al " Alpha Lipoic
Acid in Liver Metabolism and Disease", Free Radical Bioi. &
Med., 1998.
3. Sosin A., MD, Jacobs B., PhD., Alpha
Lipoic Acid. Nature's Ultimate Antioxidant, 1998.
4. Beatty, E., O'Reilly J, England, et
al., "Effect of Dietary Quercetin on Oxidative DNA Damage in Healthy
Human Subjects", Br. J. Nutr. 2000.
5. Hayashi A., Gillen A., Lott, "Effects
of Oral Administration Of Quercetin Chalcone and Modified Citrus
Pectin", Alt. Med. Rev., 2000.
6. Ishikawa V, Kitamura M., "
Anti-Apoptotic Effect of Quercetin: Intervention in the JNK and ERK
Mediated Apoptotic Pathways", Kidney Int. 2000.
7. Ginter E., "The Role of Antioxidants in
the Prevention of Tumors", Bratis Lek Listy, 1995.
8. Wiseman H. "Dietary Influences on
Membrane Function: Importance in Protection Against Oxidative Damage and
Disease", J. Ntr. Biochem, 1996.
9. Karger, S. Base, AG, "
Lipopolysaccharides and Beta-Glucuronidase Activity in Choldochal Bile
in Relation to Choledocholithiasis", International J. of
Gastroenterology, Digestion Abstract, 437, Vol. 58, No.5.
10. Walaszek Z., et al., "Metabolism,
Uptake, & Excretion of a D-Glucaric Acid Salt and its Potential Use in
Cancer Prevention", Cancer Detec. Prev., 1997.
11. Shadiz, L., Rice E., "Evaluation of
(beta) Glucuronidase Assay for the Detection of Escherichia Coli from
Environmental Waters", Canad. J. Micro., 1991.
12. "Clinical Studies with Silymarin:
Fibrosis Progression is the End Point", Hepatology- to the editor,
Feb. 2001. Voi 33, No.2.
13. Berkow R. MD. Beers, M, MD, Fletcher
A, MB.,B Chir., the Merck Manual of Med Inf., Merck Research
Lab., 1997. 14. Kline, K. et al, "Vitamin E Succinate: Mechanisms of
Action as Tumor Cell Growth Inhibitor. In Nutrients in Cancer
Prevention and Treatment.", Humana,
1995.
15. Edwards, Ken, D.C., Nutritional
Supplements...Just For The Health of It, 1998. 16. Ferenci, P.
"Therapy of Chronic Hepatitis C", Wien Med. Wochenschr, 2000.
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